Dr. Lee sees a 45-year-old woman, Ms. Carter, who has recently developed a thickened, warty appearance on her lower leg. She reports that the swelling has progressively worsened over the past 6 months and that her leg feels heavy and swollen, with no pitting. The Stemmer sign test is positive. What is the most appropriate management for this condition?

A 6-year-old boy is brought back to the GP by his mother, following a visit a week ago for an acute, widespread rash. At that time, the rash was diagnosed as allergic, with no specific trigger identified, and he was treated with an antihistamine. His mother reports no improvement and notes that he has been playing a lot in the garden due to unseasonably warm weather, but he has no history of hay fever, asthma, or eczema. He hasn’t eaten anything unusual or changed his soap or detergent. No one else in the family or their social circle has a similar rash, and he has no other symptoms, although the rash is slightly itchy.
The boy appears well and has no fever. The rash covers his trunk and, to a lesser extent, his limbs. It consists of oval patches, 1–3 cm in size, some with mild scaling along their edges, and seems to follow the skin creases. His mother recalls that one of the patches appeared on his chest about 5 days before the rash spread. What is the most likely diagnosis?